Certain groups of women have a higher risk of developing abnormal thyroid function during pregnancy. If women are in of these ‘at risk’ groups, check their thyroid levels in conception and at presentation.

Who is at risk?

History of thyroid disease or surgery Autoimmune conditions with obstetric complication Previous late pregnancy loss
  • Previous thyroid surgery
  • Type 1 diabetes mellitus
  • Stillbirth
  • Goitre
  • Systemic Lupus Erythematosus
  • Second trimester miscarriage
  • Thyroid nodule
  • Anti-Ro/Anti-La positivity
  • Two miscarriages or more
  • Previous overt or subclinical thyroid dysfunction
  • Anti-phopholipid syndrome
  • Subfertility
  • Previous thyroiditis
  • Positive TPO antibodies
  • Previous radioiodine ablation
  • Taking medication which disrupts thyroid function e.g. lithium, amiodarone
  • Previous head/neck irradiations
  • Cardiac dysrhythmia (irrregular heartbeat)
  • Significant weight loss
  • Enlarged thyroid gland
  • Thyroid nodule

Read the RCOG Green-top guideline on the Management of Thyroid Disorders in Pregnancy